CHAPTER-V Synthesis of Isoxazollyl Benzopyran Derivatives.
Synthesis of 2,3-dihydro-8-(3-hydroxy-3-methylbut-1-enyl)-7-methoxy-2-phenyl-4H-1-benzopyran-4-one: a novel structure for falciformin Virinder S. Parmar Sandhya Gupta.
The use of cyanuric chloride (2,4,6-trichloro-1,3,5-triazine) and N-methyl morpholine enables an efficient and general protocol for a rapid synthesis of substituted 3-aryl coumarins. A series of substituted phenyl acetic acids have been successfully reacted with substituted 2-hydroxy benzaldehydes to afford 3-aryl coumarins in good to excellent yields.
Keywords: 1-Benzopyran-4-one, 4-oxo-4H-1-benzopyran-3-carboxaldehyde, nucleophilic addition, dipolar cycloaddition, cyclization Table of Contents 1. Introduction 2. Decarbonylation 3. Oxidation, Reduction and Reductive Self Coupling 4. Radical Addition 5. Nucleophilic Addition 5.1.
Different alkyl amide (15a-l) and alkyl amine (16a-e) derivatives of 7,8-dimethoxy-3-hydroxy-2-(4-methoxyphenyl)benzopyran-4-one were synthesized and evaluated for their anticancer activity against five different cancer cell lines using SRB assay.
Substance Details CAS Registry Number: 117-39-5 CA Index Name: 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-.
Title:Synthesis of Benzopyran Linked Pyrrolo(2,1-c)(1,4)benzodiazepines as DNA-Binding and Potential Anticancer Agents VOLUME: 9 ISSUE: 2 Author(s):Ahmed Kamal, Rajender, Methuku Kashi Reddy, Vangala Santhosh Reddy and Gajjela Bharath Kumar Affiliation:Division of Organic Chemistry, Centre for Chemical Biology, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 607, India.
Design, synthesis and biological evaluation of novel 2-phenyl-1-benzopyran-4-one derivatives as potential poly-functional anti-Alzheimer's agents M. Singh and O. Silakari, RSC Adv., 2016, 6, 108411.